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CD14 抗体

CD14 适用: 人 FACS, WB, ELISA, Func 宿主: 小鼠 Monoclonal biG 7 unconjugated
产品编号 ABIN343172
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD14 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Functional Studies (Func)
    纯化方法
    Protein G purified
    免疫原
    Monocytes and immunoaffinity purified soluble CD14
    克隆位点
    BiG 7
    亚型
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Suitable for immunostaining of CD14 positive cells, (Flow cytometry), ELISA, Suitable for Western blot (non reducing). Non inhibition of LPS binding to CD14, binding epitope: amino acid 9-13, 39-44, Binding titre: 1:10.000
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    1 mg/ml
    缓冲液
    0.1 mg/100 ul PBS without NaN3
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Muansson, Kjaell, Pellett, Nagy, Welch, Baeckhed, Frisan, Richter-Dahlfors: "Role of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli." in: Infection and immunity, Vol. 75, Issue 2, pp. 997-1004, (2007) (PubMed).

    Neilsen, Zimmerman, McIntyre: "Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5231-9, (2001) (PubMed).

    Fan, Stelter, Menzel, Jack, Spreitzer, Hartung, Schuett: "Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction." in: Infection and immunity, Vol. 67, Issue 6, pp. 2964-8, (1999) (PubMed).

    Dziarski, Tapping, Tobias: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).

  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景
    BiG 7 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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