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CD14 抗体 (AA 147-152)

CD14 适用: 人 FACS, IF, Agon 宿主: 小鼠 Monoclonal biG2 unconjugated
产品编号 ABIN343170
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
    抗原表位
    • 16
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-152
    适用
    • 246
    • 47
    • 30
    • 29
    • 28
    • 28
    • 25
    • 24
    • 22
    • 18
    • 15
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 203
    • 64
    • 16
    • 3
    • 1
    小鼠
    克隆类型
    • 223
    • 64
    单克隆
    标记
    • 120
    • 29
    • 22
    • 17
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD14 antibody is un-conjugated
    应用范围
    • 201
    • 99
    • 61
    • 52
    • 47
    • 44
    • 22
    • 21
    • 20
    • 14
    • 13
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Agonist (Agon)
    特异性
    Soluble and membrane bound human CD14. The antibody does'nt significant block LPS binding to membrane bound CD14.
    纯化方法
    Protein G affinity column
    免疫原
    human Monocytes
    克隆位点
    BiG2
    亚型
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    no significant inhibition of LPS binding to CD14
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with bidistilled water
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.7
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
  • Stelter, Loppnow, Menzel, Grunwald, Bernheiden, Jack, Ulmer, Schuett: "Differential impact of substitution of amino acids 9-13 and 91-101 of human CD14 on soluble CD14-dependent activation of cells by lipopolysaccharide." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 11, pp. 6035-44, (1999) (PubMed).

    Dziarski, Tapping, Tobias: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).

    Neumeister, Faigle, Sommer, Zaehringer, Stelter, Menzel, Schuett, Northoff: "Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14." in: Infection and immunity, Vol. 66, Issue 9, pp. 4151-7, (1998) (PubMed).

  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景
    Background: biG 2 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
    分子量
    ~50kDa
    基因ID
    929
    NCBI登录号
    NP_000582
    UniProt
    P08571
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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