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Estrogen Receptor alpha 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects Estrogen Receptor alpha in WB 和 IP. It exhibits reactivity toward 人.
产品编号 ABIN342250
发货至: 中国
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Quick Overview for Estrogen Receptor alpha 抗体 (N-Term) (ABIN342250)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Estrogen Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    N-Term

    特异性

    Recognizes human ER-a, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-a is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER-a can positively or negatively regulate gene transcription.

    纯化方法

    Protein G purified

    免疫原

    6-His fusion protein containing the region encoding aa 1-190 of human estrogen receptor-a (ER-a) expressed in E. coli.

    Type of Immunogen: Fusion protein

    亚型

    IgG1
  • 应用备注

    Approved: IP (1 - 5 μg/mL), WB

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4

    注意事项

    Avoid freeze/thaw cycles.

    储存条件

    -80 °C

    储存方法

    Store at -70°C, avoid freeze/thaw cycles.
  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    ER Alpha / Estrogen Receptor

    背景

    Name/Gene ID: ESR1
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha

    基因ID

    2099

    UniProt

    P03372

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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