Estrogen Receptor alpha 抗体 (N-Term)
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Quick Overview for Estrogen Receptor alpha 抗体 (N-Term) (ABIN342250)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Recognizes human ER-a, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-a is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER-a can positively or negatively regulate gene transcription.
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纯化方法
- Protein G purified
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免疫原
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6-His fusion protein containing the region encoding aa 1-190 of human estrogen receptor-a (ER-a) expressed in E. coli.
Type of Immunogen: Fusion protein -
亚型
- IgG1
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应用备注
- Approved: IP (1 - 5 μg/mL), WB
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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注意事项
- Avoid freeze/thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -70°C, avoid freeze/thaw cycles.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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别名
- ER Alpha / Estrogen Receptor
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背景
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Name/Gene ID: ESR1
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha -
基因ID
- 2099
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UniProt
- P03372
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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