KLKB1 抗体
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- 抗原 See all KLKB1 抗体
- KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KLKB1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- Specifically recognizes in human plasma two variants (88 kD and 85 kD) of prekallikrein and its activation products kallikrein (88 kD and 85 kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45 kD prekallikrein/kallikrein fragment(s). It also recognizes prekallikrein and its activation products in chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80 % and 55 %, respectively. Does not cross-react with tissue kallikrein.
- 纯化方法
- Protein G purified
- 免疫原
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Human plasma prekallikrein.
Type of Immunogen: Purified protein - 克隆位点
- 13G11
- 亚型
- IgG1
- Top Product
- Discover our top product KLKB1 Primary Antibody
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- 应用备注
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Approved: ELISA, WB
Usage: May be used in ELISA and Western blots to identify/quantitate prekallikrein and its activation products in plasmas of humans, chimpanzees, rhesus monkeys, and baboons. NOTE: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples obtained from humans or other primates. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
- 别名
- KLKB1 / Plasma Kallikrein (KLKB1 产品)
- 别名
- KLK3 antibody, PPK antibody, APS antibody, Kal-3 antibody, Kal3 antibody, Klk3 antibody, PSA antibody, KALP15 antibody, Kalp1 antibody, KLKB1 antibody, DKFZp459J2015 antibody, klkb1 antibody, kallikrein B1 antibody, kallikrein B, plasma 1 antibody, plasma kallikrein antibody, Plasma kallikrein antibody, kallikrein B, plasma (Fletcher factor) 1 antibody, coagulation factor XI antibody, kallikrein B1 L homeolog antibody, KLKB1 antibody, Klkb1 antibody, CpipJ_CPIJ004042 antibody, CpipJ_CPIJ014955 antibody, CpipJ_CPIJ020108 antibody, VAA_02266 antibody, LOC100549617 antibody, klkb1 antibody, klkb1.L antibody
- 背景
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Name/Gene ID: KLKB1
Subfamily: Serine S1
Family: Protease
Synonyms: KLKB1, Fletcher factor deficiency, Fletcher factor, Kininogenin, Plasma kallikrein, PKK deficiency, Plasma kallikrein heavy chain, PPK, Prekallikrein deficiency, Plasma kallikrein light chain, Plasma prekallikrein, Kallikrein 3 - 基因ID
- 3818
- UniProt
- P03952
- 途径
- Complement System, Brown Fat Cell Differentiation
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