KLKB1 抗体
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北京 101111
Quick Overview for KLKB1 抗体 (ABIN342152)
抗原
See all KLKB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specifically recognizes in human plasma two variants (88 kD and 85 kD) of prekallikrein and its activation products kallikrein (88 kD and 85 kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45 kD prekallikrein/kallikrein fragment(s). It also recognizes prekallikrein and its activation products in chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80 % and 55 %, respectively. Does not cross-react with tissue kallikrein.
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纯化方法
- Protein G purified
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免疫原
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Human plasma prekallikrein.
Type of Immunogen: Purified protein -
亚型
- IgG1
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anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (Internal Region) antibody
KLKB1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人 ELISA, IHC, IHC (p), IEP 宿主: 绵羊 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 503-612) antibodyKLKB1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (cleaved), (Internal Region) antibodyKLKB1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 20-300) antibodyKLKB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 341-390), (Cleaved-Arg390) antibodyKLKB1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 429-478) antibodyKLKB1 适用: 人, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9F6 unconjugated Recombinant Antibody
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 391-638) antibodyKLKB1 适用: 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: ELISA, WB
Usage: May be used in ELISA and Western blots to identify/quantitate prekallikrein and its activation products in plasmas of humans, chimpanzees, rhesus monkeys, and baboons. NOTE: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples obtained from humans or other primates. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
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别名
- KLKB1 / Plasma Kallikrein
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背景
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Name/Gene ID: KLKB1
Subfamily: Serine S1
Family: Protease
Synonyms: KLKB1, Fletcher factor deficiency, Fletcher factor, Kininogenin, Plasma kallikrein, PKK deficiency, Plasma kallikrein heavy chain, PPK, Prekallikrein deficiency, Plasma kallikrein light chain, Plasma prekallikrein, Kallikrein 3 -
基因ID
- 3818
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UniProt
- P03952
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途径
- Complement System, Brown Fat Cell Differentiation
抗原
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