CEA 抗体
Quick Overview for CEA 抗体 (ABIN335404)
抗原
See all CEA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human.
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免疫原
- PARLAM 4 is a mouse monoclonal IgG1 antibody derived by fusion of Sp 2/0 Ag 14 mouse myeloma cells with spleen cells from a BABL/c mouse immunized with isolated human CEA. The immunogen has been isolated from human colonic carcinoma cells.
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亚型
- IgG1
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应用备注
- Most polyclonal CEA antisera show cross-reactivity with related antigens such as biliary glycoprotein (BGP) and non-specific cross-reacting antigen 1/11 (NCA). PARLAM 4 does not show cross reactivity, neither with BGP nor with NCA. In immunoblotting the antibody recognizes a single band of 180 kD.
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限制
- 仅限研究用
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储存条件
- 4 °C
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: "Metastatic ovarian or colonic cancer: a clinical challenge." in: European journal of cancer (Oxford, England : 1990), Vol. 28, Issue 2-3, pp. 394-9, (1992) (PubMed).
: "Use of statistical evaluation of antigen profiles in differential diagnosis between colonic and ovarian adenocarcinomas." in: Journal of clinical pathology, Vol. 41, Issue 6, pp. 644-9, (1988) (PubMed).
: "CEA-specificity of CEA-reactive monoclonal antibodies. Immunochemical and immunocytochemical studies." in: Anticancer research, Vol. 6, Issue 1, pp. 97-104, (1986) (PubMed).
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: "Metastatic ovarian or colonic cancer: a clinical challenge." in: European journal of cancer (Oxford, England : 1990), Vol. 28, Issue 2-3, pp. 394-9, (1992) (PubMed).
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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别名
- Carcinoembryonic Antigen / CEA
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背景
- This monoclonal antibody is reactive with human carcinoembryonic antigen (CEA), a tumour associated antigen with oncofetal characteristics. Although CEA can be found in tissues of non-neoplastic diseases and normal epithelia, it occurs also in a large variety of carcinomas. Therefore, immunohistochemical detection of CEA is frequently used for the histopathological diagnosis of human tumours.
抗原
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