Lamin B2 抗体
Quick Overview for Lamin B2 抗体 (ABIN335392)
抗原
See all Lamin B2 (LMNB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human, mouse, hamster and Xenopus.
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纯化方法
- Purified
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免疫原
- LN43 is a mouse monoclonal IgG1 antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with the detergent insoluble fraction of potoroo cell line PtK1.
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亚型
- IgG1
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应用备注
- LN43 reacts with an epitope located in the C-terminal part of lamin B2. LN43 is suitable for immunohistochemistry on frozen sections, immunoblotting and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
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限制
- 仅限研究用
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储存条件
- 4 °C
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A- and B-type lamins are differentially expressed in normal human tissues." in: Histochemistry and cell biology, Vol. 107, Issue 6, pp. 505-17, (1997) (PubMed).
: "Comparison of A and B-type lamin expression in reactive lymph nodes and nodular sclerosing Hodgkin's disease." in: Histopathology, Vol. 31, Issue 4, pp. 304-12, (1997) (PubMed).
: "Nuclear lamin expression in normal testis and testicular germ cell tumours of adolescents and adults." in: The Journal of pathology, Vol. 182, Issue 2, pp. 197-204, (1997) (PubMed).
: "An alternative splicing product of the lamin A/C gene lacks exon 10." in: The Journal of biological chemistry, Vol. 271, Issue 16, pp. 9249-53, (1996) (PubMed).
: "Abnormal A-type lamin organization in a human lung carcinoma cell line." in: European journal of cell biology, Vol. 67, Issue 4, pp. 328-35, (1996) (PubMed).
: "Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells." in: Journal of cell science, Vol. 108 ( Pt 2), pp. 635-44, (1995) (PubMed).
: "Nuclei that lack a lamina accumulate karyophilic proteins and assemble a nuclear matrix." in: Journal of cell science, Vol. 106 ( Pt 1), pp. 275-85, (1994) (PubMed).
: "Internal lamin structures within G1 nuclei of human dermal fibroblasts." in: Journal of cell science, Vol. 104 ( Pt 2), pp. 297-306, (1993) (PubMed).
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A- and B-type lamins are differentially expressed in normal human tissues." in: Histochemistry and cell biology, Vol. 107, Issue 6, pp. 505-17, (1997) (PubMed).
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- Lamin B2 (LMNB2)
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别名
- Lamin B2
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背景
- Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, ie lamin B1 and lamin B2.
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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