MUC1 抗体
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- 抗原 See all MUC1 抗体
- MUC1 (Mucin 1 (MUC1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MUC1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 特异性
- Human.
- 纯化方法
- Prepared from rabbit serum by affinity purification on a column made with the peptide antigen.
- 免疫原
- GP1.4 is a mouse monoclonal IgG1 antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with human milk fat globule.
- 克隆位点
- GP1-4
- 亚型
- IgG1
- Top Product
- Discover our top product MUC1 Primary Antibody
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- 应用备注
- GP1.4 reacts with all glycoforms of Episialin. APPLICATIONS GP1.4 is suitable for immunoblotting, immunocytochemistry and immunohistochemistry on frozen and paraffin-embedded tissues, and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:25 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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New immunoassays for MUC1 in breast cancer." in: Tumour biology, Vol. 22, Issue 4, pp. 216-22, (2001) (PubMed).
: "Carcinoma-associated MUC1 detected by immunoradiometric assays." in: Tumour biology, Vol. 19 Suppl 1, pp. 134-46, (1998) (PubMed).
: "Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients." in: British journal of cancer, Vol. 72, Issue 4, pp. 934-8, (1995) (PubMed).
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New immunoassays for MUC1 in breast cancer." in: Tumour biology, Vol. 22, Issue 4, pp. 216-22, (2001) (PubMed).
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- 抗原
- MUC1 (Mucin 1 (MUC1))
- 别名
- Episialin (MUC1 产品)
- 背景
- Episialin is also known as MUC1, MAM-6, CA 15-3, PEM and EMA. It is a transmembrane glycoprotein with a large mucin-like extracellular domain that matures through several intermediate forms generated by proteolysis, and sequential addition and processing of numerous O-linked glycans that are heavily sialylated. The gene encoding episialin (MUC1) is highly polymorphic and each allele encodes a product that contains a different number of repeats (between 30 and 90) leading to large differences in molecular weight of the protein. Episialin is present in several secretory epithelial cell types
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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