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Cytokeratin 18 抗体

KRT18 适用: 人, 小鼠, 大鼠, 犬, Pig, Hamster, 兔, 斑马鱼, 小鸡 WB, IHC, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RGE53 unconjugated
产品编号 ABIN335330
发货至: 中国
  • 抗原 See all Cytokeratin 18 (KRT18) 抗体
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    适用
    • 250
    • 150
    • 111
    • 43
    • 34
    • 28
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    • 21
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    • 18
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    人, 小鼠, 大鼠, 犬, Pig, Hamster, 兔, 斑马鱼, 小鸡
    宿主
    • 164
    • 121
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 151
    • 139
    单克隆
    标记
    • 142
    • 26
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    • 11
    • 9
    • 9
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    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Cytokeratin 18 antibody is un-conjugated
    应用范围
    • 215
    • 98
    • 83
    • 77
    • 74
    • 60
    • 54
    • 40
    • 38
    • 26
    • 26
    • 19
    • 8
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    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Human, mouse, rat, hamster, rabbit, chicken, canine and swine.
    纯化方法
    Purified
    免疫原
    RGE53 is a mouse monoclonal IgG1 antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with a cytoskeletal preparation of cells.
    克隆位点
    RGE53
    亚型
    IgG1
    Top Product
    Discover our top product KRT18 Primary Antibody
  • 应用备注
    RGE53 reacts exclusively with cytokeratin 18 which is present in glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them. RGE53 is suitable for immunoblotting, immunocytochemistry, immunohistochemistry on frozen sections and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
    限制
    仅限研究用
  • 储存条件
    4 °C
  • van Leenders, Dijkman, Hulsbergen-van de Kaa, Ruiter, Schalken: "Demonstration of intermediate cells during human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopy." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 80, Issue 8, pp. 1251-8, (2000) (PubMed).

    Smedts, Ramaekers, Troyanovsky, Pruszczynski, Link, Lane, Leigh, Schijf, Vooijs: "Keratin expression in cervical cancer." in: The American journal of pathology, Vol. 141, Issue 2, pp. 497-511, (1992) (PubMed).

    Ramaekers, van Niekerk, Poels, Schaafsma, Huijsmans, Robben, Schaart, Vooijs: "Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas." in: The American journal of pathology, Vol. 136, Issue 3, pp. 641-55, (1990) (PubMed).

    Smedts, Ramaekers, Robben, Pruszczynski, van Muijen, Lane, Leigh, Vooijs: "Changing patterns of keratin expression during progression of cervical intraepithelial neoplasia." in: The American journal of pathology, Vol. 136, Issue 3, pp. 657-68, (1990) (PubMed).

    Raats, Pieper, Vree Egberts, Verrijp, Ramaekers, Bloemendal: "Assembly of amino-terminally deleted desmin in vimentin-free cells." in: The Journal of cell biology, Vol. 111, Issue 5 Pt 1, pp. 1971-85, (1990) (PubMed).

    Puts, Moesker, Kenemans, Vooijs, Ramaekers: "Expression of cytokeratins in early neoplastic epithelial lesions of the uterine cervix." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 4, Issue 4, pp. 300-13, (1986) (PubMed).

    Ramaekers, Puts, Moesker, Kant, Huysmans, Haag, Jap, Herman, Vooijs: "Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview." in: The Histochemical journal, Vol. 15, Issue 7, pp. 691-713, (1983) (PubMed).

    Ramaekers, Huysmans, Moesker, Kant, Jap, Herman, Vooijs: "Monoclonal antibody to keratin filaments, specific for glandular epithelia and their tumors. Use in surgical pathology." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 49, Issue 3, pp. 353-61, (1983) (PubMed).

  • 抗原
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    别名
    Cytokeratin 18 / Keratin K18 (KRT18 产品)
    别名
    CK18 antibody, K18 antibody, Krt1-18 antibody, CYK18 antibody, DreK18 antibody, cb83 antibody, dapk1 antibody, sb:cb83 antibody, wu:fa13f02 antibody, wu:fb36b04 antibody, krt18 antibody, MGC64569 antibody, MGC75922 antibody, KRT18 antibody, CK-18-A antibody, K18-A antibody, NC-11 antibody, cyk18 antibody, k18 antibody, krt18-a antibody, krt18-b antibody, krt18a antibody, xkendob antibody, keratin 18 antibody, keratin 18, type I L homeolog antibody, keratin 18, type I antibody, keratin, type I cytoskeletal 18 antibody, K18, simple type I keratin antibody, Keratin, type I cytoskeletal 18 antibody, keratin 18, type I S homeolog antibody, Krt18 antibody, KRT18 antibody, krt18 antibody, krt18.L antibody, LOC700569 antibody, LOC100136778 antibody, k1c18 antibody, LOC100008885 antibody, krt18.S antibody
    背景
    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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