MUC1 抗体
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北京 101111
Quick Overview for MUC1 抗体 (ABIN3222739)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).
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产品特性
- Host: Hybridization of P3X63-Ag8.653, myeloma cells with spleen cells from Balb/c mice.
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纯化方法
- Purified by Protein A chromatography
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纯度
- > 98 % pure
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免疫原
- Human breast cancer cell line ZR 75-1
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亚型
- IgG1
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应用备注
- Capture or detection antibody in serological assays for the research of antigen MUC-1. Forms a suitable pair withX108 , Catalog # L1C00802. Immunohistochemistry on frozen or paraffin sections for the detection of MUC-1. Immunochemical detection of MUC-1 protein.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1:1000~5000
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缓冲液
- 150mM NaCl 10mM Tris, pH7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- MUC1 (Mucin 1 (MUC1))
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别名
- CA15-3
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背景
- Monoclonal Antibody to Carbohydrate Antigen 15-3(CA15-3) (Breast Cancer)
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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