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MUC1 抗体

This 小鼠 单克隆 antibody specifically detects MUC1 in IHC (p) 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN3222739
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MUC1 抗体 (ABIN3222739)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).

    产品特性

    Host: Hybridization of P3X63-Ag8.653, myeloma cells with spleen cells from Balb/c mice.

    纯化方法

    Purified by Protein A chromatography

    纯度

    > 98 % pure

    免疫原

    Human breast cancer cell line ZR 75-1

    亚型

    IgG1
  • 应用备注

    Capture or detection antibody in serological assays for the research of antigen MUC-1. Forms a suitable pair withX108 , Catalog # L1C00802. Immunohistochemistry on frozen or paraffin sections for the detection of MUC-1. Immunochemical detection of MUC-1 protein.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1:1000~5000

    缓冲液

    150mM NaCl 10mM Tris, pH7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    CA15-3

    背景

    Monoclonal Antibody to Carbohydrate Antigen 15-3(CA15-3) (Breast Cancer)

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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