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CD59 抗体 (PE)

This anti-CD59 antibody is a 小鼠 单克隆 antibody detecting CD59 in FACS. Suitable for 人.
产品编号 ABIN320332
发货至: 中国

Quick Overview for CD59 抗体 (PE) (ABIN320332)

抗原

See all CD59 抗体
CD59

适用

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宿主

  • 91
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小鼠

克隆类型

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  • 1
单克隆

标记

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This CD59 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-43-5
  • 特异性

    This antibody reacts with a PI-linked glycoprotein, Mw 18-20 kDa found on all types of leucocytes including platelets. The antigen is expressed on many haemopoietic and non-haemopoietic cells.

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein A

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: Use 10 μL of Neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.25 mL distilled water.

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted Prior to and after reconstitution at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch. Reconstitution: Restore with 1.0 ml distilled water..

    有效期

    12 months
  • 抗原

    CD59

    别名

    CD59

    背景

    CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

    基因ID

    966

    UniProt

    P13987

    途径

    Complement System
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