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E2F1 抗体 (pSer364)

E2F1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal #2 unconjugated
产品编号 ABIN3201010
发货至: 中国
  • 抗原 See all E2F1 抗体
    E2F1 (E2F Transcription Factor 1 (E2F1))
    抗原表位
    • 25
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    • 18
    • 15
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    • 12
    • 10
    • 8
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    • 6
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    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    pSer364
    适用
    • 206
    • 100
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    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 210
    • 11
    • 2
    小鼠
    克隆类型
    • 201
    • 22
    单克隆
    标记
    • 92
    • 17
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    • 10
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    • 5
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    • 2
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    This E2F1 antibody is un-conjugated
    应用范围
    • 186
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    Western Blotting (WB), ELISA
    产品特性
    Product: Mouse monoclonal antibody (clone #2) specific to the human E2F1 protein phosphorylated at Ser364. Produced in serum-free medium and purified under mild conditions
    纯化方法
    Purified
    免疫原
    A synthetic peptide corresponding to a sequence of human E2F1 protein including and surrounding pSer364
    克隆位点
    #2
    亚型
    IgG2b kappa
    Top Product
    Discover our top product E2F1 Primary Antibody
  • 应用备注
    1. Western blotting: ~1 g/mL
    2. ELISA
    Not tested for other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (-), 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C/-80 °C
    储存方法
    -20 C (For long term storage: -70 C)
  • Trimarchi, Lees: "Sibling rivalry in the E2F family." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 1, pp. 11-20, (2002) (PubMed).

    Irwin, Marin, Phillips, Seelan, Smith, Liu, Flores, Tsai, Jacks, Vousden, Kaelin: "Role for the p53 homologue p73 in E2F-1-induced apoptosis." in: Nature, Vol. 407, Issue 6804, pp. 645-8, (2000) (PubMed).

  • 抗原
    E2F1 (E2F Transcription Factor 1 (E2F1))
    别名
    E2F1 (E2F1 产品)
    别名
    CG6376 antibody, DRTF1/E2F antibody, DmE2F-1 antibody, Dmel\\CG6376 antibody, Dp antibody, E(Sev-CycE)3A antibody, E(var)3-93E antibody, E(var)3-95E antibody, E(var)93E antibody, E2F antibody, E2F-1 antibody, E2F1 antibody, E2f1 antibody, Evar(3)164 antibody, dE2F antibody, dE2F1 antibody, dE2f antibody, dE2f1 antibody, de2f1 antibody, def21 antibody, drosE2F1 antibody, e2f antibody, e2f1 antibody, l(3)07172 antibody, l(3)j3B1 antibody, l(3)j3C2 antibody, l(3)rM729 antibody, RBAP1 antibody, RBBP3 antibody, RBP3 antibody, mKIAA4009 antibody, xE2F antibody, ATE2FB antibody, E2F TRANSCRIPTION FACTOR-1 E2F1 antibody, E2F transcription factor 1 antibody, E2FB antibody, E2FB TRANSCRIPTION FACTOR antibody, E2F transcription factor 1 antibody, E2F transcription factor 1 L homeolog antibody, E2f1 antibody, E2F1 antibody, e2f1.L antibody
    背景
    E2F1 is a member of E2F group of proteins that share common structural and functional domains and plays a major role during the G1/S transition in the mammalian cell cycle as a transcriptional factor. E2F1 is regulated during cell cycle progression. It is phosphorylated at Ser364 by Chk2 kinase in response to DNA damage, stabilized, mobilized to nucleus and activated as a transcription factor. It induces apoptosis by activating transcription of the p53 homolog, p73. E2F1 protein consists of 437 amino acids with a molecular mass of 46 kDa.
    UniProt
    Q01094
    途径
    p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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