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E2F1 抗体 (pSer364)

Name: E2F1 抗体 (pSer364)
SKU: ABIN3201010
Availability: OutOfStock

This anti-E2F1 antibody is a 小鼠单克隆 antibody detecting E2F1 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western Blotting (WB) image for anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibody (ABIN3201010) (E2F1 抗体 (pSer364))

1 image

(2 references)

产品编号 ABIN3201010

发货至: 中国

Quick Overview for E2F1 抗体 (pSer364) (ABIN3201010)

抗原

See all E2F1 抗体

E2F1 (E2F Transcription Factor 1 (E2F1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This E2F1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

克隆位点

Discover our top product E2F1 Primary Antibody

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pSer364

产品特性

Product: Mouse monoclonal antibody (clone #2) specific to the human E2F1 protein phosphorylated at Ser364. Produced in serum-free medium and purified under mild conditions

纯化方法

Purified

免疫原

A synthetic peptide corresponding to a sequence of human E2F1 protein including and surrounding pSer364

亚型

IgG2b kappa
anti-E2F Transcription Factor 1 (E2F1) (AA 69-223) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8G9 unconjugated

anti-E2F Transcription Factor 1 (E2F1) antibody
E2F1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 1D12 unconjugated Recombinant Antibody

anti-E2F Transcription Factor 1 (E2F1) (AA 348-437) antibody
E2F1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2E10 unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibody
E2F1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibody
E2F1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) antibody
E2F1 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibody
E2F1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibody
E2F1 适用: 人 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (pThr433) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (C-Term) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

1. Western blotting: ~1 g/mL
2. ELISA
Not tested for other applications.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PBS (-), 50 % glycerol

储存液

Azide free

储存条件

-20 °C/-80 °C

储存方法

-20 C (For long term storage: -70 C)
Trimarchi, Lees: "Sibling rivalry in the E2F family." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 1, pp. 11-20, (2002) (PubMed).

Irwin, Marin, Phillips, Seelan, Smith, Liu, Flores, Tsai, Jacks, Vousden, Kaelin: "Role for the p53 homologue p73 in E2F-1-induced apoptosis." in: Nature, Vol. 407, Issue 6804, pp. 645-8, (2000) (PubMed).
抗原

E2F1 (E2F Transcription Factor 1 (E2F1))

别名

E2F1

背景

E2F1 is a member of E2F group of proteins that share common structural and functional domains and plays a major role during the G1/S transition in the mammalian cell cycle as a transcriptional factor. E2F1 is regulated during cell cycle progression. It is phosphorylated at Ser364 by Chk2 kinase in response to DNA damage, stabilized, mobilized to nucleus and activated as a transcription factor. It induces apoptosis by activating transcription of the p53 homolog, p73. E2F1 protein consists of 437 amino acids with a molecular mass of 46 kDa.

UniProt

Q01094

途径

p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy