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CD59 抗体 (FITC)

This anti-CD59 antibody is a 小鼠 单克隆 antibody detecting CD59 in FACS. Suitable for 人.
产品编号 ABIN319789
发货至: 中国

Quick Overview for CD59 抗体 (FITC) (ABIN319789)

抗原

See all CD59 抗体
CD59

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This CD59 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-43
  • 特异性

    The antigen binds to C8 and C9 and inhibits assembly of the complement membrane attack complex.

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein A

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry (Neat).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    BS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD59

    别名

    CD59

    背景

    CD59 is an LY6 like protein expressed in human lymphoid cells (haemapoietic and non- haemapoietic cells), regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. CD59 is an 18-20kD GPI anchored single chain glycoprotein, expressed by virtually all cell types, including leucocytes, platelets and erythrocytes.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

    基因ID

    966

    NCBI登录号

    NP_000602

    UniProt

    P13987

    途径

    Complement System
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