HDAC2 抗体 (pSer394)
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Quick Overview for HDAC2 抗体 (pSer394) (ABIN319237)
抗原
See all HDAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer394
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特异性
- This antibody HDAC2 (pSer394) detects endogenous levels of HDAC2 only when phosphorylated at Serine 394.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic phosphopeptide derived from human HDAC2 around the phosphorylation site of serine 394 (E-D-SP-G-D).
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应用备注
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Western blot (1/500-1/1000). Immunohistochemistry (1/50-1/100). Immunofluorescence (1/100-1/200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C.
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- HDAC2 (Histone Deacetylase 2 (HDAC2))
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别名
- HDAC2
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背景
- Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.Synonyms: HD2, Histone deacetylase 2
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基因ID
- 3066
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NCBI登录号
- NP_001518
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UniProt
- Q92769
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途径
- Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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