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ASK1 抗体 (C-Term)

MAP3K5 适用: 人 WB, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318975
发货至: 中国
  • 抗原 See all ASK1 (MAP3K5) 抗体
    ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
    抗原表位
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    C-Term
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This ASK1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises ASK1 (Apoptosis signal-regulating kinase 1) a 155 kDa protein belonging to the protein kinase superfamily.
    纯化方法
    Purified
    免疫原
    A peptide corresponding to amino acids near the carboxy terminus of human ASK1.
    亚型
    IgG
    Top Product
    Discover our top product MAP3K5 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 155 kDa in SW1353 celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
    别名
    MEKK5 / ASK1 (MAP3K5 产品)
    别名
    ASK1 antibody, MAPKKK5 antibody, MEKK5 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MUD21.11 antibody, MUD21_11 antibody, 7420452D20Rik antibody, ASK antibody, Mekk5 antibody, Ask1 antibody, RGD1306565 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MAP3K5 antibody, MAPKKK5 antibody, Map3k5 antibody, map3k5 antibody
    背景
    ASK1 is a serine/threonine kinase, also known as MAP kinase kinase kinase (MAPKKK), and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis. ASK1 is widely expressed in a variety of human tissues including the heart and pancreas.Synonyms: Apoptosis signal-regulating kinase 1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, Mitogen-activated protein kinase kinase kinase 5
    基因ID
    4217
    NCBI登录号
    NP_005914
    UniProt
    Q99683
    途径
    MAPK Pathway, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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