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ALOX5 抗体 (pSer523)

ALOX5 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318947
发货至: 中国
  • 抗原 See all ALOX5 抗体
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    抗原表位
    • 16
    • 15
    • 15
    • 11
    • 9
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer523
    适用
    • 86
    • 77
    • 58
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 猴
    宿主
    • 100
    • 9
    • 1
    克隆类型
    • 100
    • 10
    多克隆
    标记
    • 44
    • 11
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    This ALOX5 antibody is un-conjugated
    应用范围
    • 58
    • 39
    • 39
    • 26
    • 25
    • 14
    • 9
    • 6
    • 6
    • 5
    • 4
    • 2
    Western Blotting (WB)
    特异性
    This antibody specifically recognises human 5-lipoxygenase (5-LO, also known as arachidonate 5-lipoxygenase) when phosphorylated at Ser523.
    纯化方法
    Purified
    免疫原
    Synthetic phosphopeptide corresponding to an amino acid sequence within human 5-lipoxygenase which includes phosphorylated Ser523.
    亚型
    IgG
    Top Product
    Discover our top product ALOX5 Primary Antibody
  • 应用备注
    Western Blot: 1: 1000, detects a doublet of approximately 80 kDa in rat cortex lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES pH 7.5, 150 mM NaCl containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin, 50 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    别名
    ALOX5 / LOG5 (ALOX5 产品)
    别名
    5-LO antibody, 5-LOX antibody, 5LPG antibody, LOG5 antibody, 5LO antibody, 5LX antibody, AI850497 antibody, F730011J02 antibody, LOX5A antibody, si:dkey-194n13.2 antibody, lox5 antibody, arachidonate 5-lipoxygenase antibody, arachidonate 5-lipoxygenase a antibody, Arachidonate 5-lipoxygenase antibody, ALOX5 antibody, Alox5 antibody, alox5a antibody, AFUA_4G02770 antibody, AOR_1_1362014 antibody, lox5 antibody
    背景
    5-LO is an enzyme that catalyses the synthesis of leukotrienes (LT's) from arachidonic acid (a polyunsaturated fatty acid), by the insertion of an oxygen into the arachidonic backbone. 5-LO requires calcium, ATP and the 5LOactivating protein as cofactors for full activity. Leukotrienes are synthesised and secreted by leukocytes in response to immunologic or inflammatory stimuli, such as in asthma and allergic reactions. The biological effects of LT's include leukocyte chemotaxis, pulmonary airway constriction, mucous hypersecretion, vasoconstriction and increased vascular permeability. I recent years 5-LO has also been implicated in the regulation of cell proliferation and apoptosis and has been found in a broad variety of cancer cells.Synonyms: 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase
    基因ID
    240
    NCBI登录号
    NP_000689
    UniProt
    P09917
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