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CD44 抗体

This anti-CD44 antibody is a 山羊 多克隆 antibody detecting CD44 in IHC (fro). Suitable for 人.
产品编号 ABIN318928
发货至: 中国

Quick Overview for CD44 抗体 (ABIN318928)

抗原

See all CD44 抗体
CD44

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    This antibody specifically recognises epitopes encoded by exons v3-v10 on the variant portion of CD44.

    纯化方法

    Purified

    免疫原

    Recombinant human CD44v3-v10

    亚型

    IgG
  • 应用备注

    Immunohistochemistry on frozen sections: 50g/mL. Immunohistochemistry on paraffin sections: 20g/mL, requires antigen retrieval using heattreatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 isrecommended for this purpose. Positive Control: Breast carcinoma and colon adenocarcinoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0mg/mL

    缓冲液

    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD44

    别名

    CD44

    背景

    CD44 is a ubiquitously expressed type 1 transmembrane glycoprotein and proteoglycan, otherwise known as phagocytic glycoprotein 1 (pgp 1), which acts as a receptor for the major extracellular matrix component hyaluronate, and also binds other ligands including collagen and matrix metalloproteinases (MMPs). CD44 is known to play a role in cell-cell interactions, cell adhesion, the activation and homing of lymphocytes, cell migration, haematopoiesis and metastasis, and exists as a number of isoforms generated by the alternative RNA splicing of at least 10 variant exons (CD44v).Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I

    基因ID

    960

    NCBI登录号

    NP_000601

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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