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MAP2K5 抗体 (pSer311, pThr315)

MAP2K5 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 斑马鱼, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318850
发货至: 中国
  • 抗原 See all MAP2K5 抗体
    MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
    抗原表位
    • 28
    • 28
    • 16
    • 15
    • 15
    • 15
    • 9
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer311, pThr315
    适用
    • 130
    • 58
    • 54
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 小鸡, 斑马鱼, 非洲爪蟾, 猴
    宿主
    • 142
    • 6
    克隆类型
    • 133
    • 15
    多克隆
    标记
    • 44
    • 11
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    This MAP2K5 antibody is un-conjugated
    应用范围
    • 113
    • 66
    • 65
    • 50
    • 19
    • 15
    • 14
    • 12
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody specifically recognises 49 kDa MEK5, also known as MAP2K5, when phosphorylated at Ser311 and Thr315. Activation of MEK5 itself is regulated by upstream MAP3K3/MEKK3, and phosphorylation of MEK5 at both the Ser311 and Thr315 sites has been implicated in cell proliferation.
    纯化方法
    Purified
    免疫原
    Synthetic phosphopeptide corresponding to an amino acid sequence within MEK5 , which includes phoshorylated Ser311 and Thr315.
    亚型
    IgG
    Top Product
    Discover our top product MAP2K5 Primary Antibody
  • 应用备注
    Western Blot: 1: 1000, detects a band of approximately 49 kDa in rat testes cell lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 0.01 % Bovine Serum Albumin, 50 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
    别名
    MAP2K5 (MAP2K5 产品)
    别名
    Mek5 antibody, HsT17454 antibody, MAPKK5 antibody, MEK5 antibody, PRKMK5 antibody, AI324775 antibody, AI428457 antibody, Mapkk5 antibody, Prkmk5 antibody, fb73f02 antibody, wu:fb73f02 antibody, zgc:172137 antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 antibody, ATMAP2K_ALPHA antibody, ATMEK5 antibody, ATMKK5 antibody, MAP KINASE KINASE 5 antibody, MAP kinase kinase 5 antibody, MAP2K_A antibody, mitogen activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 L homeolog antibody, MAP kinase kinase 5 antibody, Map2k5 antibody, MAP2K5 antibody, map2k5 antibody, map2k5.L antibody, MKK5 antibody
    背景
    MEK5 is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family, which acts as a key regulator in a mitogen-activated protein (MAP) kinase cascade, and hence growth factor-induced cellular stimulation. MEK5 exists in naturally occurring MEK5alpha and MEK5beta splice variants, the former of which is known to specifically activate/regulate MAPK7/ERK5/BMK1, whilst the latter may act as a suppressor of MAPK7 activation.Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MEK5, MKK5
    基因ID
    5607
    NCBI登录号
    NP_001193733
    UniProt
    Q13163
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway
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