MAP2K5 抗体 (pSer311, pThr315)
Quick Overview for MAP2K5 抗体 (pSer311, pThr315) (ABIN318850)
抗原
See all MAP2K5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer311, pThr315
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特异性
- This antibody specifically recognises 49 kDa MEK5, also known as MAP2K5, when phosphorylated at Ser311 and Thr315. Activation of MEK5 itself is regulated by upstream MAP3K3/MEKK3, and phosphorylation of MEK5 at both the Ser311 and Thr315 sites has been implicated in cell proliferation.
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纯化方法
- Purified
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免疫原
- Synthetic phosphopeptide corresponding to an amino acid sequence within MEK5 , which includes phoshorylated Ser311 and Thr315.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 251-350) antibody
MAP2K5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-448) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-E6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 385-412), (C-Term) antibodyMAP2K5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (pSer137) antibodyMAP2K5 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 311-315) antibodyMAP2K5 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1: 1000, detects a band of approximately 49 kDa in rat testes cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 0.01 % Bovine Serum Albumin, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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别名
- MAP2K5
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背景
- MEK5 is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family, which acts as a key regulator in a mitogen-activated protein (MAP) kinase cascade, and hence growth factor-induced cellular stimulation. MEK5 exists in naturally occurring MEK5alpha and MEK5beta splice variants, the former of which is known to specifically activate/regulate MAPK7/ERK5/BMK1, whilst the latter may act as a suppressor of MAPK7 activation.Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MEK5, MKK5
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基因ID
- 5607
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NCBI登录号
- NP_001193733
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UniProt
- Q13163
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway
抗原
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