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EGFR 抗体 (AA 1189-1199)

The 兔 多克隆 anti-EGFR antibody (ABIN318810) specifically detects EGFR in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN318810
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EGFR 抗体 (AA 1189-1199) (ABIN318810)

抗原

See all EGFR 抗体
EGFR (Epidermal Growth Factor Receptor (EGFR))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This EGFR antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 1189-1199

    特异性

    This antibody detects human epidermal growth factor receptor (EGFR).

    纯化方法

    Purified

    免疫原

    Synthetic peptide corresponding to amino acids 1189-1199 of human EGF receptor protein.

    亚型

    IgG
  • 应用备注

    ELISA: 1: 8000 - 1: 32000. Western Blot: 1: 500 - 1: 5000, detects a band of approximately 170 kDa in A431 cell lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0mg/mL

    缓冲液

    Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    别名

    EGFR / ERBB1

    背景

    EGFR is a 170kD transmembrane glycoprotein which is a member of the ErbB family of receptor tyrosine kinases. EGFR is the cell surface receptor for members of the EGF family, and functions in early embryonic development and in the renewal of stem cells in tissues such as the skin, liver and gut. Mutations to EGFR have been found in many human carcinomas including breast, brain, lung, and colon. Over-expression of more than one member of the ErbB family was found to have a negative synergistic effect on patient outcome.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1

    基因ID

    1956

    NCBI登录号

    NP_005219

    UniProt

    P00533

    途径

    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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