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EGFR 抗体 (AA 1189-1199)
EGFR
适用: 人, 小鼠, 大鼠
WB, EIA
宿主: 兔
Polyclonal
unconjugated
EGFR抗体详情
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抗原
See all EGFR 抗体
EGFR
(Epidermal Growth Factor Receptor (EGFR))
抗原表位
All epitopes for EGFR 抗体
AA 1189-1199
适用
All reactivities for EGFR 抗体
人, 小鼠, 大鼠
宿主
All hosts for EGFR 抗体
兔
克隆类型
All clonalities for EGFR 抗体
多克隆
标记
All conjugates for EGFR 抗体
This EGFR antibody is un-conjugated
应用范围
All applications for EGFR 抗体
Western Blotting (WB), Enzyme Immunoassay (EIA)
特异性
This antibody detects human epidermal growth factor receptor (EGFR).
纯化方法
Purified
免疫原
Synthetic peptide corresponding to amino acids 1189-1199 of human EGF receptor protein.
亚型
IgG
Top Product
Discover our top product EGFR Primary Antibody
Alternatives
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anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR
适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊
WB
宿主: 山羊
Polyclonal
unconjugated
使用细节
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应用备注
ELISA: 1: 8000 - 1: 32000. Western Blot: 1: 500 - 1: 5000, detects a band of approximately 170 kDa in A431 cell lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
1.0mg/mL
缓冲液
Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
EGFR目标详情
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抗原
EGFR
(Epidermal Growth Factor Receptor (EGFR))
别名
EGFR / ERBB1 (EGFR 产品 )
别名
C-erb antibody, CG10079 antibody, D-EGFR antibody, D-Egf antibody, DEGFR antibody, DER antibody, DER flb antibody, DER/EGFR antibody, DER/faint little ball antibody, DER/top antibody, DER/torpedo antibody, DER1 antibody, DEgfr antibody, Degfr antibody, Der antibody, DmHD-33 antibody, Dmel\\CG10079 antibody, EFG-R antibody, EGF-R antibody, EGFR antibody, EGFr antibody, EGfr antibody, EK2-6 antibody, Egf antibody, Egf-r antibody, EgfR antibody, El antibody, Elp antibody, Elp-1 antibody, Elp-B1 antibody, Elp-B1RB1 antibody, HD-33 antibody, TOP antibody, Torpedo/DER antibody, Torpedo/Egfr antibody, c-erbB antibody, d-egf-r antibody, dEGFR antibody, dEGFR1 antibody, dEgfr antibody, der antibody, egfr antibody, flb antibody, l(2)05351 antibody, l(2)09261 antibody, l(2)57DEFa antibody, l(2)57EFa antibody, l(2)57Ea antibody, mor1 antibody, top antibody, top/DER antibody, top/flb antibody, torpedo/Egfr antibody, torpedo/egfr antibody, EGFR12 antibody, EGFR15 antibody, egfr1 antibody, Erbb2 antibody, ERBB antibody, ERBB1 antibody, HER1 antibody, PIG61 antibody, mENA antibody, ErbB-1 antibody, Errp antibody, 9030024J15Rik antibody, AI552599 antibody, Erbb antibody, Errb1 antibody, Wa5 antibody, wa-2 antibody, wa2 antibody, epidermal growth factor receptor antibody, Epidermal growth factor receptor antibody, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody, EGFR antibody, Egfr antibody, egfra antibody, egfr1 antibody, LOC5564544 antibody
背景
EGFR is a 170kD transmembrane glycoprotein which is a member of the ErbB family of receptor tyrosine kinases. EGFR is the cell surface receptor for members of the EGF family, and functions in early embryonic development and in the renewal of stem cells in tissues such as the skin, liver and gut. Mutations to EGFR have been found in many human carcinomas including breast, brain, lung, and colon. Over-expression of more than one member of the ErbB family was found to have a negative synergistic effect on patient outcome.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
基因ID
1956
NCBI登录号
NP_005219
UniProt
P00533
途径
NF-kappaB Signaling , RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Stem Cell Maintenance , Hepatitis C , Positive Regulation of Response to DNA Damage Stimulus , Interaction of EGFR with phospholipase C-gamma , Thromboxane A2 Receptor Signaling , EGFR Downregulation , S100 Proteins
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