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MAPT 抗体 (pSer396)

This anti-MAPT antibody is a 兔多克隆 antibody detecting MAPT in WB 和 EIA. Suitable for 人, 大鼠和小鼠.

Image no. 2 for anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibody (ABIN318142) (MAPT 抗体 (pSer396))

Image no. 1 for anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibody (ABIN318142) (MAPT 抗体 (pSer396))

2 images

产品编号 ABIN318142

发货至: 中国

Quick Overview for MAPT 抗体 (pSer396) (ABIN318142)

抗原

See all MAPT 抗体

MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

216
17
6
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This MAPT antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

Discover our top product MAPT Primary Antibody

抗原表位
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1
pSer396

纯化方法

Affinity Chromatography using epitope-specific immunogen.
anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer262) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer235) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (AA 130-386) antibody
MAPT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (AA 34-368) antibody
MAPT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
MAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer356) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

MAPT (Microtubule-Associated Protein tau (MAPT))

别名

MAPT / tau

背景

Tau is a neuronal microtubule associated protein found predominantly on axons. The function of Tau is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. Tau, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Hyperphosphorylation impairs the microtubule binding function of Tau, resulting in the destabilisation of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons. Hyperphosphorylated tau is also found in a range of other central nervous system disorders. Numerous serine/threonine kinases, including GSK3 beta, PKA, Cdk5, and casein kinase II can phosphorylate Tau.Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau

基因ID

9606

UniProt

P10636

途径

MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size

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