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Plakophilin 2 抗体

The 兔 多克隆 anti-Plakophilin 2 antibody (ABIN317928) specifically detects Plakophilin 2 in WB. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN317928
发货至: 中国
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Quick Overview for Plakophilin 2 抗体 (ABIN317928)

抗原

See all Plakophilin 2 (PKP2) 抗体
Plakophilin 2 (PKP2)

适用

  • 49
  • 21
  • 20
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 42
  • 4
  • 2
  • 1

克隆类型

  • 45
  • 4
多克隆

标记

  • 32
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Plakophilin 2 antibody is un-conjugated

应用范围

  • 36
  • 23
  • 21
  • 7
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. Western blot: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Plakophilin 2 (PKP2)

    别名

    Plakophilin-2

    背景

    Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.Synonyms: PKP2

    分子量

    approx. 97 kDa

    基因ID

    9606

    UniProt

    Q99959

    途径

    Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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