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MAPK6 抗体

The 兔 多克隆 anti-MAPK6 antibody is suitable to detect MAPK6 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN317885
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAPK6 抗体 (ABIN317885)

抗原

See all MAPK6 抗体
MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MAPK6 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    ERK3 antibody detects endogenous levels of ERK3 protein.(region surrounding Lys185)

    纯化方法

    Affinity chromatography
  • 应用备注

    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

    别名

    MAPK6 / ERK3

    背景

    Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl2 and caspase 3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK3 gene maps to chromosome 15q21 and encodes a 721 amino acid protein.Synonyms: Extracellular signal-regulated kinase 3, MAP kinase isoform p97, Mitogen-activated protein kinase 6, Serine/threonine-protein kinase, p97-MAPK

    分子量

    approx. 83 kDa

    基因ID

    5597

    NCBI登录号

    NP_002739

    UniProt

    Q16659

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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