CSF1R 抗体
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北京 101111
Quick Overview for CSF1R 抗体 (ABIN317880)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- M-CSF Receptor antibody detects endogenous levels of M-CSF Receptor protein.(region surrounding Gln718)
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纯化方法
- Affinity chromatography
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CD115
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背景
- This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
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分子量
- approx. 108 kDa
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基因ID
- 1436
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NCBI登录号
- NP_005202
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UniProt
- P07333
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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