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LPAR3 抗体

LPAR3 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317747
发货至: 中国
  • 抗原 See all LPAR3 抗体
    LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
    适用
    • 38
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    宿主
    • 42
    克隆类型
    • 42
    多克隆
    标记
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    This LPAR3 antibody is un-conjugated
    应用范围
    • 16
    • 16
    • 14
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    EDG-7 antibody detects endogenous levels of EDG-7 protein.(region surrounding Pro324)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product LPAR3 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
    别名
    EDG-7 / LPAR3 (LPAR3 产品)
    别名
    EDG7 antibody, Edg-7 antibody, GPCR antibody, HOFNH30 antibody, LP-A3 antibody, LPA3 antibody, RP4-678I3 antibody, Edg7 antibody, lpA3 antibody, lysophosphatidic acid receptor 3 antibody, LPAR3 antibody, LOC100038016 antibody, Lpar3 antibody
    背景
    The EDG (endothelial differentiation gene) family of G protein-coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.Synonyms: EDG7, Endothelial differentiation, GPCR, HOFNH3O, LPA-3, LPAR3, Lysophosphatidic acid receptor 3, Lysophosphatidic acid receptor Edg-7, lysophosphatidic acid G-protein coupled receptor 7
    分子量
    approx. 47 kDa
    基因ID
    23566
    NCBI登录号
    NP_036284
    UniProt
    Q9UBY5
    途径
    Regulation of Cell Size
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