LPAR3 抗体
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北京 101111
Quick Overview for LPAR3 抗体 (ABIN317747)
抗原
See all LPAR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- EDG-7 antibody detects endogenous levels of EDG-7 protein.(region surrounding Pro324)
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纯化方法
- Affinity chromatography
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anti-Lysophosphatidic Acid Receptor 3 (LPAR3) antibody
LPAR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (Internal Region) antibodyLPAR3 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (AA 101-200) antibodyLPAR3 适用: 人, 小鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (C-Term) antibodyLPAR3 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) antibodyLPAR3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (Internal Region) antibodyLPAR3 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (AA 1-12) antibodyLPAR3 适用: 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (Cytoplasmic Domain) antibodyLPAR3 适用: 人, 小鼠, 大鼠, 猴, Bat, Cow, 犬, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (AA 16-29), (Extracellular) antibodyLPAR3 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 3 (LPAR3) (AA 312-330) antibodyLPAR3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
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别名
- EDG-7 / LPAR3
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背景
- The EDG (endothelial differentiation gene) family of G protein-coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.Synonyms: EDG7, Endothelial differentiation, GPCR, HOFNH3O, LPA-3, LPAR3, Lysophosphatidic acid receptor 3, Lysophosphatidic acid receptor Edg-7, lysophosphatidic acid G-protein coupled receptor 7
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分子量
- approx. 47 kDa
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基因ID
- 23566
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NCBI登录号
- NP_036284
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UniProt
- Q9UBY5
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途径
- Regulation of Cell Size
抗原
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