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FZD9 抗体

FZD9 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317735
发货至: 中国
  • 抗原 See all FZD9 抗体
    FZD9 (Frizzled Family Receptor 9 (FZD9))
    适用
    • 77
    • 30
    • 22
    • 11
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 76
    • 1
    克隆类型
    • 77
    多克隆
    标记
    • 37
    • 5
    • 5
    • 4
    • 3
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This FZD9 antibody is un-conjugated
    应用范围
    • 52
    • 37
    • 13
    • 13
    • 12
    • 8
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Frizzled-9 antibody detects endogenous levels of Frizzled-9 protein.(region surrounding Leu591)
    纯化方法
    Affinity-chromatography
    Top Product
    Discover our top product FZD9 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FZD9 (Frizzled Family Receptor 9 (FZD9))
    别名
    CD349 / FZD9 / Frizzled-9 (FZD9 产品)
    别名
    CD349 antibody, FZD3 antibody, mfz9 antibody, Fz-9 antibody, cFz-9 antibody, fz11 antibody, fzd9 antibody, fzx antibody, hm:zehl0603 antibody, zehl0603 antibody, zg11 antibody, frizzled class receptor 9 antibody, frizzled class receptor 9a antibody, frizzled class receptor 9b antibody, FZD9 antibody, Fzd9 antibody, fzd9a antibody, fzd9b antibody
    背景
    The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins (FRPs) have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. The frizzled-9 gene is located within the Williams Syndrome common deleted region at chromosomal band 7q11.23. Heterozygous deletion of the frizzled-9 gene may contribute to the Williams Syndrome phenotype. In mouse, frizzled-9 overexpression can induce the hyperphosphorylation and relocalization of Dvl-1 from the cytoplasm to the cell membrane and cytosolic β-catenin accumulation. In rat, frizzled-9 is important in Wnt/β-catenin signaling in 293T cells. Frizzled-9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.Synonyms: Fz-9, hFz9
    分子量
    approx. 64 kDa
    基因ID
    8326
    NCBI登录号
    NP_003499
    UniProt
    O00144
    途径
    WNT signaling
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