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FZD9 抗体

This anti-FZD9 antibody is a 兔 多克隆 antibody detecting FZD9 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN317735
发货至: 中国

Quick Overview for FZD9 抗体 (ABIN317735)

抗原

See all FZD9 抗体
FZD9 (Frizzled Family Receptor 9 (FZD9))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FZD9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    Frizzled-9 antibody detects endogenous levels of Frizzled-9 protein.(region surrounding Leu591)

    纯化方法

    Affinity-chromatography
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FZD9 (Frizzled Family Receptor 9 (FZD9))

    别名

    CD349 / FZD9 / Frizzled-9

    背景

    The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins (FRPs) have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. The frizzled-9 gene is located within the Williams Syndrome common deleted region at chromosomal band 7q11.23. Heterozygous deletion of the frizzled-9 gene may contribute to the Williams Syndrome phenotype. In mouse, frizzled-9 overexpression can induce the hyperphosphorylation and relocalization of Dvl-1 from the cytoplasm to the cell membrane and cytosolic β-catenin accumulation. In rat, frizzled-9 is important in Wnt/β-catenin signaling in 293T cells. Frizzled-9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.Synonyms: Fz-9, hFz9

    分子量

    approx. 64 kDa

    基因ID

    8326

    NCBI登录号

    NP_003499

    UniProt

    O00144

    途径

    WNT signaling
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