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FZD7 抗体

This anti-FZD7 antibody is a 兔 多克隆 antibody detecting FZD7 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN317734
发货至: 中国

Quick Overview for FZD7 抗体 (ABIN317734)

抗原

See all FZD7 抗体
FZD7 (Frizzled Family Receptor 7 (FZD7))

适用

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人, 小鼠

宿主

  • 46
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克隆类型

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多克隆

标记

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This FZD7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Frizzled-7 protein.(region surrounding Tyr87)

    纯化方法

    Affinity Chromatography.
  • 应用备注

    ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % Sodium Azide as preservative, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FZD7 (Frizzled Family Receptor 7 (FZD7))

    别名

    FZD7 / Frizzled-7

    背景

    The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. frizzled-7 has a Lys-Thr-X-X-X-Trp motif which is involved in the activation of the Wnt/beta-catenin signaling pathway. frizzled-7 is an integral membrane protein showing a high expression in adult skeletal muscle, fetal kidney, fetal lung, adult heart, brain and placenta. It is specifically expressed in squamous cell esophageal carcinomas.Synonyms: Fz-7, mFz7

    基因ID

    8324

    NCBI登录号

    NP_003498

    UniProt

    O75084

    途径

    WNT signaling, Stem Cell Maintenance
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