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PTH1R 抗体

This anti-PTH1R antibody is a 兔 多克隆 antibody detecting PTH1R in WB, IF, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN317698
发货至: 中国

Quick Overview for PTH1R 抗体 (ABIN317698)

抗原

See all PTH1R 抗体
PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

适用

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人, 大鼠, 小鼠

宿主

  • 41
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克隆类型

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多克隆

标记

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This PTH1R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of PTH/PTHrP-R protein.(region surrounding Leu187)

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse and Rat.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

    别名

    PTH Receptor 1

    背景

    Parathyroid Hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino-terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy.Synonyms: PTH/PTHrP type I receptor, PTH1R, PTHR, PTHR1, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor

    分子量

    approx. 52 kDa

    基因ID

    5745

    NCBI登录号

    NP_000307

    UniProt

    Q03431

    途径

    Regulation of Carbohydrate Metabolic Process
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