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FZD10 抗体

The 兔 多克隆 anti-FZD10 antibody is suitable to detect FZD10 in samples from 人 和 小鼠. It has been validated for WB, IF, IHC (p) 和 EIA.
产品编号 ABIN317639
发货至: 中国
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Quick Overview for FZD10 抗体 (ABIN317639)

抗原

See all FZD10 抗体
FZD10 (Frizzled Family Receptor 10 (FZD10))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FZD10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Frizzled-10 protein.(region surrounding Leu164)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/5000-1/10000. Wetern Blot: 1/500-1/1000. Immunofuorescence: 1/50-1/200. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FZD10 (Frizzled Family Receptor 10 (FZD10))

    别名

    CD350 / FZD10 / Frizzled-10

    背景

    This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.Frizzled 10 is expressed during development in embryonic limbs, neural tube, and central nervous system. It has been reported to be expressed in brain, embryo, kidney, liver, lung and pancreas.Synonyms: Fz-10, FzE7, hFz10

    分子量

    approx. 60 kDa

    基因ID

    11211

    NCBI登录号

    NP_009128

    UniProt

    Q9ULW2

    途径

    WNT signaling
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