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FZD1 抗体

Fzd1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317638
发货至: 中国
  • 抗原 See all FZD1 (Fzd1) 抗体
    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
    适用
    • 38
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 5
    • 3
    • 1
    克隆类型
    • 39
    • 6
    多克隆
    标记
    • 29
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD1 antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 12
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of Frizzled-1 protein.(region surrounding Leu55)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product Fzd1 Primary Antibody
  • 应用备注
    ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
    别名
    FZD1 / Frizzled-1 (Fzd1 产品)
    别名
    CG17697 antibody, CG3646 antibody, DFZ1 antibody, DFz antibody, DFz1 antibody, Dfz1 antibody, Dm Fz1 antibody, Dmel\\CG17697 antibody, FZ antibody, Frz antibody, Fz antibody, Fz1 antibody, frz antibody, fz1 antibody, fz[[1]] antibody, Fz-1 antibody, cFz-1 antibody, Xfrizzled-1 antibody, frizzled1 antibody, frz-1 antibody, frz1 antibody, fzd1-A antibody, AW227548 antibody, FZ-1 antibody, frizzled antibody, frizzled class receptor 1 antibody, frizzled class receptor 1 L homeolog antibody, fz antibody, FZD1 antibody, Fzd1 antibody, fzd1.L antibody
    背景
    The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.Synonyms: Fz-1, FzE1, hFz1
    分子量
    approx. 71 kDa
    基因ID
    8321
    NCBI登录号
    NP_003496
    UniProt
    Q9UP38
    途径
    WNT signaling, Asymmetric Protein Localization
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