FZD1 抗体
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北京 101111
Quick Overview for FZD1 抗体 (ABIN317638)
抗原
See all FZD1 (Fzd1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Frizzled-1 protein.(region surrounding Leu55)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Frizzled Family Receptor 1 (Fzd1) (AA 117-322) antibody
Fzd1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 73-322) antibodyFzd1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 367-396) antibodyFzd1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14325 unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 374-404), (Middle Region) antibodyFzd1 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (N-Term) antibodyFzd1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (N-Term) antibodyFzd1 适用: 人, 小鼠, 大鼠, Bat, Cow, 犬, Hamster, 马, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 504-533), (C-Term) antibodyFzd1 适用: 人 WB 宿主: 兔 Polyclonal RB14327 unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (AA 369-400), (C-Term) antibodyFzd1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) antibodyFzd1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 1 (Fzd1) (N-Term) antibodyFzd1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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别名
- FZD1 / Frizzled-1
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背景
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.Synonyms: Fz-1, FzE1, hFz1
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分子量
- approx. 71 kDa
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基因ID
- 8321
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NCBI登录号
- NP_003496
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UniProt
- Q9UP38
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途径
- WNT signaling, Asymmetric Protein Localization
抗原
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