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S1PR1 抗体

This 兔 多克隆 antibody specifically detects S1PR1 in WB, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN317632
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for S1PR1 抗体 (ABIN317632)

抗原

See all S1PR1 抗体
S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This S1PR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of EDG-1 protein.(region surrounding Thr48)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

    别名

    EDG-1 / S1PR1

    背景

    EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG1 leads to increased cell-cell aggregation and overexpression of cadherins. EDG1 transcripts have been reported to be present in embryonic and adult brain, lung alveolar macrophages, vascular smooth muscle cells, endothelial cells, fibroblasts and melanocytes but to be absent from breast cancer cell lines.Synonyms: CHEDG1, D1S3362, ECGF1, EDG1, Endothelial differentiation G-protein coupled receptor 1, FLJ58121, S1P receptor 1, S1PR1, Sphingosine 1-phosphate receptor 1

    分子量

    approx. 43 kDa

    基因ID

    1901

    NCBI登录号

    NP_001391

    UniProt

    P21453

    途径

    Signaling Events mediated by VEGFR1 and VEGFR2
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