AKAP13 抗体
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北京 101111
Quick Overview for AKAP13 抗体 (ABIN317612)
抗原
See all AKAP13 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AKAP13 Protein.(region surrounding Asp738)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))
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别名
- AKAP13
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背景
- AKAP13 functions as a protein kinase A (PKA)-anchoring protein and acts as an adapter protein to selectively couple G alpha-13 and Rho. It contains a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins. AKAP13 augments gene activation by the estrogen receptor and activates estrogen receptor beta by a p38 MAPK-dependent pathway. AKAP13 is involved in the signaling pathways leading to cardiomyocytes hypertrophy.Synonyms: A-kinase anchor protein 13, AKAP-Lbc, BRX, Breast cancer nuclear receptor-binding auxiliary protein, Guanine nucleotide exchange factor Lbc, HT31, Human thyroid-anchoring protein 31, LBC, Lymphoid blast crisis oncogene, Non-oncogenic Rho GTPase-specific GTP exchange factor, P47, Protein kinase A-anchoring protein 13
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基因ID
- 11214
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NCBI登录号
- NP_006729
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UniProt
- Q12802
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途径
- Neurotrophin Signaling Pathway
抗原
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