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CSF1R 抗体 (PE)

CSF1R 适用: 小鼠, 大鼠 FACS 宿主: 大鼠 Monoclonal 604B5 2E11 PE
产品编号 ABIN317385
发货至: 中国
  • 抗原 See all CSF1R 抗体
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    适用
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    小鼠, 大鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CSF1R antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes the CD115 cell surface antigen, also known as the M-CSF receptor and as c-fms. This antibody has been shown to inhibit in vitro colony formation in response to M-CSF in both rats and mice.
    交叉反应 (详细)
    Species reactivity (tested):Mouse and Rat.
    产品特性
    Synonyms: CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1receptor
    纯化方法
    Purified IgG prepared by ion exchange chromatography
    免疫原
    RAW 264 cells. Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653myeloma cell line.
    克隆位点
    604B5 2E11
    亚型
    IgG1
    Top Product
    Discover our top product CSF1R Primary Antibody
  • 应用备注
    Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.0 mL distilled water.
    缓冲液
    PBS, 0.09 % Sodium Azide, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    别名
    CD115 (CSF1R 产品)
    别名
    AI323359 antibody, CD115 antibody, CSF-1R antibody, Csfmr antibody, Fim-2 antibody, Fms antibody, M-CSF-R antibody, M-CSFR antibody, C-FMS antibody, CSFR antibody, FIM2 antibody, FMS antibody, HDLS antibody, PDGFRB antibody, MGC89146 antibody, CSF-1-R antibody, c-fms antibody, mrfms antibody, CSF1 antibody, M-CSF antibody, csf1r antibody, fms antibody, panther antibody, colony stimulating factor 1 receptor antibody, macrophage colony-stimulating factor receptor antibody, colony stimulating factor 1 receptor, a antibody, Csf1r antibody, CSF1R antibody, m-csfr antibody, csf1r antibody, csf1ra antibody
    背景
    CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (M-CSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain. CD115 is expressed by cells of the monocytic lineage and by progenitor cells.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
    基因ID
    12978
    UniProt
    P09581
    途径
    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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