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CSF1R 抗体 (PE)

This anti-CSF1R antibody is a 大鼠 单克隆 antibody detecting CSF1R in FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN317385
发货至: 中国

Quick Overview for CSF1R 抗体 (PE) (ABIN317385)

抗原

See all CSF1R 抗体
CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

适用

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小鼠, 大鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CSF1R antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

604B5 2E11
  • 特异性

    This antibody recognizes the CD115 cell surface antigen, also known as the M-CSF receptor and as c-fms. This antibody has been shown to inhibit in vitro colony formation in response to M-CSF in both rats and mice.

    交叉反应 (详细)

    Species reactivity (tested):Mouse and Rat.

    产品特性

    Synonyms: CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1receptor

    纯化方法

    Purified IgG prepared by ion exchange chromatography

    免疫原

    RAW 264 cells. Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653myeloma cell line.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.0 mL distilled water.

    缓冲液

    PBS, 0.09 % Sodium Azide, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

    别名

    CD115

    背景

    CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (M-CSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain. CD115 is expressed by cells of the monocytic lineage and by progenitor cells.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms

    基因ID

    12978

    UniProt

    P09581

    途径

    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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