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CSF1R 抗体

CSF1R 适用: 小鼠, 大鼠 FACS, Func 宿主: 大鼠 Monoclonal 604B5 2E11 unconjugated
产品编号 ABIN317381
发货至: 中国
  • 抗原 See all CSF1R 抗体
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    适用
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    小鼠, 大鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CSF1R antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    This antibody recognizes the Murine CD115 cell surface antigen, also known as the M-CSF receptor and as c-fms. This antibody has been shown to inhibit in vitro colony formation in response to M-CSF in both rats and mice.
    产品特性
    Synonyms: CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1receptor
    纯化方法
    Purified IgG prepared by ion exchange chromatography
    免疫原
    RAW 264 cells. Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653myeloma cell line.
    克隆位点
    604B5 2E11
    亚型
    IgG1
    Top Product
    Discover our top product CSF1R Primary Antibody
  • 应用备注
    Functional Assays. Flow Cytometry: Use 10 μL of 1/10-1/100 diluted antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, None, None
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    别名
    CD115 (CSF1R 产品)
    别名
    AI323359 antibody, CD115 antibody, CSF-1R antibody, Csfmr antibody, Fim-2 antibody, Fms antibody, M-CSF-R antibody, M-CSFR antibody, C-FMS antibody, CSFR antibody, FIM2 antibody, FMS antibody, HDLS antibody, PDGFRB antibody, MGC89146 antibody, CSF-1-R antibody, c-fms antibody, mrfms antibody, CSF1 antibody, M-CSF antibody, csf1r antibody, fms antibody, panther antibody, colony stimulating factor 1 receptor antibody, macrophage colony-stimulating factor receptor antibody, colony stimulating factor 1 receptor, a antibody, Csf1r antibody, CSF1R antibody, m-csfr antibody, csf1r antibody, csf1ra antibody
    背景
    This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
    基因ID
    12978
    UniProt
    P09581
    途径
    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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