Cytochrome C 抗体
-
- 抗原 See all Cytochrome C (CYCS) 抗体
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
-
适用
- 人, 大鼠, 小鼠, 兔
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Cytochrome C antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- 特异性
- This antiobdy recognises cytochrome c, originally termed Apaf-2, an evolutionarily conserved protein which acts as an essential mitochondrial electron carrier between respirable substrates and oxygen, during aerobic energy production. Clone 2G8 is reported to block the role of cytochrome c as a co-factor in the activation of caspase 9. Removal of sodium azide is recommended prior to use in functional assays
- 产品特性
- Synonyms: CYCS, CYC
- 纯化方法
- Purified IgG prepared by affinity chromatography on Protein A
- 免疫原
- Human cytochrome c
- 克隆位点
- 2G8
- 亚型
- IgG1
- Top Product
- Discover our top product CYCS Primary Antibody
-
-
- 应用备注
-
Flow Cytometry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only. - 有效期
- 12 months
-
- 抗原
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
- 别名
- Cytochrome C (CYCS 产品)
- 背景
- A second major function for cytochrome c is its role as an intermediate in apoptosis, both through its association with inositol-3-phosphate receptor (IP3 receptor) which acts as an ER calcium release channel, and its association with apoptotic protease activating factor 1 (Apaf-1), resulting in the formation of the apoptosome protein complex which then recruits and activates pro-caspase 9 (Apaf-3).Synonyms: CYC, CYCS
- 基因ID
- 54205
- UniProt
- P99999
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
-