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Cytochrome C 抗体

CYCS 适用: 人, 大鼠, 小鼠, 兔 FACS, EIA 宿主: 小鼠 Monoclonal 2G8 unconjugated
产品编号 ABIN317119
发货至: 中国
  • 抗原 See all Cytochrome C (CYCS) 抗体
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    适用
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    人, 大鼠, 小鼠, 兔
    宿主
    • 89
    • 65
    • 6
    • 1
    小鼠
    克隆类型
    • 83
    • 77
    • 1
    单克隆
    标记
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    This Cytochrome C antibody is un-conjugated
    应用范围
    • 126
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    Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antiobdy recognises cytochrome c, originally termed Apaf-2, an evolutionarily conserved protein which acts as an essential mitochondrial electron carrier between respirable substrates and oxygen, during aerobic energy production. Clone 2G8 is reported to block the role of cytochrome c as a co-factor in the activation of caspase 9. Removal of sodium azide is recommended prior to use in functional assays
    产品特性
    Synonyms: CYCS, CYC
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein A
    免疫原
    Human cytochrome c
    克隆位点
    2G8
    亚型
    IgG1
    Top Product
    Discover our top product CYCS Primary Antibody
  • 应用备注
    Flow Cytometry. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
    有效期
    12 months
  • 抗原
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    别名
    Cytochrome C (CYCS 产品)
    背景
    A second major function for cytochrome c is its role as an intermediate in apoptosis, both through its association with inositol-3-phosphate receptor (IP3 receptor) which acts as an ER calcium release channel, and its association with apoptotic protease activating factor 1 (Apaf-1), resulting in the formation of the apoptosome protein complex which then recruits and activates pro-caspase 9 (Apaf-3).Synonyms: CYC, CYCS
    基因ID
    54205
    UniProt
    P99999
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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