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Cytochrome C 抗体

This 小鼠 单克隆 anti-Cytochrome C antibody (Clone 2G8) specifically detects Cytochrome C in FACS 和 EIA. The antibody is reactive with 人, 大鼠, 小鼠 和 兔 samples.
产品编号 ABIN317119
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cytochrome C 抗体 (ABIN317119)

抗原

See all Cytochrome C (CYCS) 抗体
Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

适用

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人, 大鼠, 小鼠, 兔

宿主

  • 118
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  • 5
  • 1
小鼠

克隆类型

  • 160
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  • 1
单克隆

标记

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This Cytochrome C antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

2G8
  • 特异性

    This antiobdy recognises cytochrome c, originally termed Apaf-2, an evolutionarily conserved protein which acts as an essential mitochondrial electron carrier between respirable substrates and oxygen, during aerobic energy production. Clone 2G8 is reported to block the role of cytochrome c as a co-factor in the activation of caspase 9. Removal of sodium azide is recommended prior to use in functional assays

    产品特性

    Synonyms: CYCS, CYC

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein A

    免疫原

    Human cytochrome c

    亚型

    IgG1
  • 应用备注

    Flow Cytometry. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

    有效期

    12 months
  • 抗原

    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

    别名

    Cytochrome C

    背景

    A second major function for cytochrome c is its role as an intermediate in apoptosis, both through its association with inositol-3-phosphate receptor (IP3 receptor) which acts as an ER calcium release channel, and its association with apoptotic protease activating factor 1 (Apaf-1), resulting in the formation of the apoptosome protein complex which then recruits and activates pro-caspase 9 (Apaf-3).Synonyms: CYC, CYCS

    基因ID

    54205

    UniProt

    P99999

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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