POMC 抗体 (N-Term)
Quick Overview for POMC 抗体 (N-Term) (ABIN316639)
抗原
See all POMC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-24, N-Term
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特异性
- This ACTH antibody (Clone 57, BGN/1388/66) recognises 1-24 ACTH (Synacthen) which, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. It does not recognise 17-39 ACTH (CLIP). Cross-reacts with Rat N-terminal ACTH.
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产品特性
- Synonyms: Corticotropin, Adrenocorticotropic hormone, ACTH
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纯化方法
- Purified IgG prepared by affinity chromatography on Protein A
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免疫原
- Synthetic peptide corresponding to the amino acids 1-24 of the Human ACTH conjugated toKeyhole Limpet Haemocyanin. AA Sequence: SYSMEHFRWGKPVGKKRRPVKVYP
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亚型
- IgG1
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anti-Proopiomelanocortin (POMC) (C-Term) antibody
Verified POMC 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (N-Term) antibodyPOMC 适用: 人, 小鼠, 大鼠 ELISA, IHC, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal 57 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D2B5 unconjugated
anti-Proopiomelanocortin (POMC) antibodyPOMC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 205-267) antibodyPOMC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D3A10 unconjugated
anti-Proopiomelanocortin (POMC) (AA 138-176), (Middle Region) antibodyPOMC 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: 1/100-1/200(Requires protein digestion pre-treatment of paraffin sections e. g. trypsin or pronase).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2, containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- POMC (Proopiomelanocortin (POMC))
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别名
- POMC
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背景
- ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC
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基因ID
- 5443
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UniProt
- P01189
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
抗原
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