CD59 抗体 (Biotin)
Quick Overview for CD59 抗体 (Biotin) (ABIN3071864)
抗原
See all CD59 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD59 Biotin Antibody
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产品特性
- The clone BRA-10G binds with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis and is a potent inhibitor of the complement membrane attack complex. CD59 is widely distributed on cells in all tissues. The CD59 expression on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human K562 tumor cells
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS pH 7.2, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD59
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别名
- CD59
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NCBI登录号
- NP_000602, NP_001120695, NP_001120697, NP_001120698, NP_001120699, NP_976074, NP_976075, NP_976076
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UniProt
- P13987
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途径
- Complement System
抗原
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