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FAK 抗体 (C-Term)

This anti-FAK antibody is a 兔 多克隆 antibody detecting FAK in WB 和 IP. Suitable for 小鼠.
产品编号 ABIN306813
发货至: 中国

Quick Overview for FAK 抗体 (C-Term) (ABIN306813)

抗原

See all FAK (PTK2) 抗体
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This FAK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    C-Term

    交叉反应

    小鼠

    产品特性

    Focal Adhesion Kinase (FAK) is a 120 kDa tyrosine kinase which become phosphorylated in response to oncogene- and extracellular-matrix integrin-dependent stimulation. Chicken, mouse and human FAK has been isolated and the deduced amino acid sequences showed identity of over 90 % . It is expressed in embryonic stem cells, and ubiquitously throughout development, in all adult tissues examined and in many cell lines. The highest expression of FAK is seen in the brain, testes and in osteoclasts. It is distinct from other non-receptor protein tyrosine kinases in that its catalytic domain is flanked by amino- and carboxy-terminal domains of about 400 amino acids each. Also, it does not contain the Src homology 2 or 3 domains, which mediate protein-protein interaction, nor a myristylation site that anchors proteins to the membrane.

    纯化方法

    Ammonium Sulfate Precipitation

    免疫原

    Bacterially expressed fusion protein consisting of the C-terminal 150 amino acids of the mouse FAK

    亚型

    IgG
  • 应用备注

    Detect focal adhesion kinase by IP/Western analysis in BALB/c 3T3 fibroblasts1. Detects a 120 kDa band. Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 缓冲液

    Provided as solution in phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    别名

    Focal Adhesion Kinase (FAK)

    UniProt

    P34152

    途径

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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