LPAR3 抗体 (C-Term)
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Quick Overview for LPAR3 抗体 (C-Term) (ABIN306802)
抗原
See all LPAR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti Human Lysophosphatidic Acid Receptor 3 CT (EDG-7)
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交叉反应
- 人
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产品特性
- Endothelial Cell Differentiation Gene-7 (EDG-7) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-7 is lysophospholipid. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Antibody raised against a unique synthetic peptide derived from the C-terminal of the human EDG7 protein.
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亚型
- IgG
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应用备注
- Detects recombinant EDG-7 receptors by Western blot. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
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别名
- Lysophosphatidic Acid Receptor 3 CT (EDG-7)
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背景
- Endothelial cell differentiation gene 7 C-terminal, Lysophosphatidic Acid Receptor-4 (LPA3)
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UniProt
- Q9UBY5
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途径
- Regulation of Cell Size
抗原
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