VAV2 抗体
Our Local Distributor
北京 101111
Quick Overview for VAV2 抗体 (ABIN306673)
抗原
See all VAV2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
亚型
- IgG
-
-
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 552-868) antibody
VAV2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F5D3 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyKD Validated VAV2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3270 unconjugated Recombinant Antibody
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56694 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (Internal Region) antibodyVerified VAV2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 108-157), (pTyr142) antibodyVAV2 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 570-700) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 612-691) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (Tyr299) antibodyVAV2 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
浓度
- 1mg/ml
-
-
- VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))
-
别名
- Vav-2 DPH
-
背景
- The immunogen used for the anti-human Vav-2 DPH region was a his tagged fusion protein Vav-2 corresponding to amino acid sequence 287-578 and having a molecular weight of 100kD. Vav-2 has a molecular weight of 100 kD and shares over a 50% homology at the amino acid and nucleic acid level with Vav. Vav-2 is a ubiquitously expressed structural homolog of the Vav protooncogene that is expressed preferentially in hematopoetiic cells. Both proteins are comprised of a Dbl- homology ((DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type vav-2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a Vav-2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokenesis frequently are uncoupled. Synonyms: VAV-2, Guanine nucleotide exchange factor VAV-2, Dbl homology (DH) domain.
-
UniProt
- P52735
-
途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
-
