p130 抗体
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北京 101111
Quick Overview for p130 抗体 (ABIN306630)
抗原
See all p130 (RBL2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti Human p130
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产品特性
- P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.
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纯化方法
- Protein A/G Chromatography
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亚型
- IgG1
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应用备注
- Western Blots at 1:1000
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限制
- 仅限研究用
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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别名
- p130
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背景
- P130, Retinoblastoma-like protein 2, RBR-2, PRB2
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分子量
- 130kDa
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UniProt
- Q08999, Q64700, O55081
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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