ErbB2/Her2 抗体 (full length)
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北京 101111
Quick Overview for ErbB2/Her2 抗体 (full length) (ABIN306627)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- full length
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原理
- Sheep anti Human HER2/neu
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产品特性
- c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25 % of primary breast and ovarian tumors were found to overexpress the protein.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Full-length recombinant c-erbB-2/HER2/neu protein.
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亚型
- IgG
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应用备注
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
- c-ErbB-2
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背景
- P185erbB2, MLN 19, CD340, c-ErbB-2
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UniProt
- P04626
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
抗原
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