CDC25A 抗体
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北京 101111
Quick Overview for CDC25A 抗体 (ABIN306562)
抗原
See all CDC25A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti Human CDC25A
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产品特性
- The immunogen for the anti CDC25A was a purified recombinant CDC25A protein recognizing a 65kD protein. In the cell cycle of eukaryotes the M phase is initiated by maturation promoting factor (MPF), a protein kinase complex consisting of p34 cdc2, cyclin B, and p13. The activity of this complex is controlled by multiple levels of phosphorylation and dephosphorylation of the catalytic p34cdc2 component. CDC25A and CDC25B arep34cdc2 tyrosine phosphates. Dephosphorylation of p34cdc2 by these CDC25 proteins activates the MPF complex, initiating mitosis. Although expressed throughout the cell cycle, peak expression of CDC25A is in G1 of the cell cycle.
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纯化方法
- Protein A/G Chromatography
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亚型
- IgG2a
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应用备注
- Western Blot, Immunoprecipitation at 1-10 μg/mL
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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别名
- CDC25A
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背景
- Dual specificity phosphatase Cdc25A, M-phase inducer phosphatase 1, MPIP1,
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UniProt
- P30304
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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