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CD44 抗体 (AA 21-145)

This anti-CD44 antibody is a 小鼠 单克隆 antibody detecting CD44 in FACS, WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN306452
发货至: 中国

Quick Overview for CD44 抗体 (AA 21-145) (ABIN306452)

抗原

See all CD44 抗体
CD44

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

5C10
  • 抗原表位

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    AA 21-145

    纯化方法

    The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

    免疫原

    Recombinant human CD44 (21-145aa) purified from E. coli

    亚型

    IgG2b kappa
  • 应用备注

    Recommended dilution 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    CD44

    别名

    CD44

    背景

    CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.

    NCBI登录号

    NP_001001390

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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