CD44 抗体 (AA 21-145)
Quick Overview for CD44 抗体 (AA 21-145) (ABIN306452)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-145
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纯化方法
- The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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免疫原
- Recombinant human CD44 (21-145aa) purified from E. coli
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亚型
- IgG2b kappa
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应用备注
- Recommended dilution 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD44
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别名
- CD44
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背景
- CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.
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NCBI登录号
- NP_001001390
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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