Integrin beta 3 抗体 (PE)
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- 抗原 See all Integrin beta 3 (ITGB3) 抗体
- Integrin beta 3 (ITGB3)
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适用
- 小鼠, 大鼠
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宿主
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仓鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 3 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
- 纯化方法
- Protein G purified
- 免疫原
- Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
- 亚型
- IgG
- Top Product
- Discover our top product ITGB3 Primary Antibody
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- 应用备注
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Approved: Flo (1:1 - 1:10), IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Distilled Water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze.
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- 抗原
- Integrin beta 3 (ITGB3)
- 别名
- ITGB3 / Integrin beta 3 / CD61 (ITGB3 产品)
- 背景
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Name/Gene ID: ITGB3
Family: Integrin
Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3 - 基因ID
- 3690
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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