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beta Actin 抗体 (N-Term)

ACTB 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044573
发货至: 中国
  • 抗原 See all beta Actin (ACTB) 抗体
    beta Actin (ACTB) (Actin, beta (ACTB))
    抗原表位
    • 40
    • 18
    • 16
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-19, N-Term
    适用
    • 189
    • 133
    • 120
    • 64
    • 51
    • 44
    • 37
    • 36
    • 32
    • 25
    • 20
    • 20
    • 12
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    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 113
    • 92
    • 5
    • 2
    • 1
    克隆类型
    • 107
    • 104
    多克隆
    标记
    • 132
    • 15
    • 14
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This beta Actin antibody is un-conjugated
    应用范围
    • 178
    • 76
    • 58
    • 50
    • 37
    • 33
    • 28
    • 24
    • 13
    • 13
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Actin, cytoplasmic 1(ACTB) detection. Tested with WB in Human,Mouse,Rat.
    序列
    DDDIAALVVD NGSGMCKA
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Actin, cytoplasmic 1(ACTB) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: actin, beta
    Protein Name: Actin, cytoplasmic 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human beta Actin(2-19aaDDDIAALVVDNGSGMCKA), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product ACTB Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
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    Zuo, Liu, Zhang, Wu, Guo, Liao: "Development of trastuzumab-resistant human gastric carcinoma cell lines and mechanisms of drug resistance." in: Scientific reports, Vol. 5, pp. 11634, (2015) (PubMed).

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    Wang, Wu, Wang, Tian, Chen, Li: "The biophysical property of A549 cells transferred by VEGF-D." in: Scanning, Vol. 36, Issue 2, pp. 202-8, (2015) (PubMed).

    Lee, Lee, Huo, Wang, Huang, Lin, Chuang, Lee: "Diabetes enhances the intrahepatic vascular response to endothelin-1 in cirrhotic rats: association with the ETA receptor and pERK up-regulation." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 35, Issue 3, pp. 704-12, (2015) (PubMed).

    Qiao, Wei, Dai, Zhou, Yin, Li, Xiao, Guo, Lu: "UCP2-related mitochondrial pathway participates in oroxylin A-induced apoptosis in human colon cancer cells." in: Journal of cellular physiology, Vol. 230, Issue 5, pp. 1054-63, (2015) (PubMed).

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    Shi, Yang, Mao, Wu, Ren, Yang, Yin, Wei, Li, Wang: "Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation." in: Acta pharmacologica Sinica, Vol. 36, Issue 2, pp. 252-8, (2015) (PubMed).

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    Wang, Li, Tang, Yang, Wang, Liu, Yang, Yang: "Overexpression of Tiam1 promotes the progression of laryngeal squamous cell carcinoma." in: Oncology reports, Vol. 33, Issue 4, pp. 1807-14, (2015) (PubMed).

    Fu, Lin, Liang, Hu: "Effects of recombinant baculovirus AcMNPV-BmK IT on the formation of early cables and nuclear polymerization of actin in Sf9 cells." in: Cytotechnology, (2015) (PubMed).

    Wang, Gai, Xu, Zheng, Lv, Li, Liu: "Shikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathway." in: International journal of clinical and experimental pathology, Vol. 8, Issue 1, pp. 298-308, (2015) (PubMed).

    Rong, Ding, Zhang, Guo: "Neuregulin1? improves cognitive dysfunction and up-regulates expression of p-ERK1/2 in rats with chronic omethoate poisoning." in: Behavioral and brain functions : BBF, Vol. 11, pp. 5, (2015) (PubMed).

    Yang, Yan, Liu, Wang, Hu: "Protective effects of acteoside against X?ray?induced damage in human skin fibroblasts." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 2301-6, (2015) (PubMed).

    Shi, Wu, Wang, Zhou, Yan, Chen, Gu, Cai: "Liquiritigenin Potentiates the Inhibitory Effects of Cisplatin on Invasion and Metastasis Via Downregulation MMP-2/9 and PI3 K/AKT Signaling Pathway in B16F10 Melanoma Cells and Mice Model." in: Nutrition and cancer, Vol. 67, Issue 5, pp. 761-70, (2015) (PubMed).

    Zhao, Wang, Meng, Ji, Xu, Chen, Fan, Yu, Yao, Dong: "MicroRNA-27a-3p Inhibits Melanogenesis in Mouse Skin Melanocytes by Targeting Wnt3a." in: International journal of molecular sciences, Vol. 16, Issue 5, pp. 10921-33, (2015) (PubMed).

  • 抗原
    beta Actin (ACTB) (Actin, beta (ACTB))
    别名
    ACTB (ACTB 产品)
    别名
    BRWS1 antibody, PS1TP5BP1 antibody, ACTA1 antibody, Actx antibody, E430023M04Rik antibody, beta-actin antibody, ps1tp5bp1 antibody, act-2 antibody, actb antibody, B-actin antibody, LOC100174883 antibody, LOC100304816 antibody, A antibody, ACT5C antibody, Ac5C antibody, Act antibody, Act-5C antibody, Act5 antibody, Act5c antibody, Actin antibody, Actin/BAP47 antibody, Actin5C antibody, BAP47 antibody, Bap47 antibody, CG4027 antibody, Dmel\\CG4027 antibody, M32055 antibody, T11 antibody, act antibody, act 5C antibody, act5C antibody, actin antibody, actin5C antibody, anon-EST:fe2D2 antibody, beta-actin/Bap47 antibody, cyt5C antibody, l(1)G0009 antibody, l(1)G0010 antibody, l(1)G0025 antibody, l(1)G0079 antibody, l(1)G0117 antibody, l(1)G0177 antibody, l(1)G0245 antibody, l(1)G0330 antibody, l(1)G0420 antibody, l(1)G0486 antibody, Bact antibody, ACT-5 antibody, ACTB antibody, B-ACTZF antibody, actba antibody, bact antibody, bactin1 antibody, bactzf antibody, wu:fd18f05 antibody, A26C1B antibody, POTE2alpha antibody, POTEACTIN antibody, Beta-actin antibody, actin beta antibody, actin, beta antibody, cytoplasmic actin OlCA1 antibody, beta-actin antibody, Actin 5C antibody, actin gamma 1 antibody, actin, beta 1 antibody, actin, beta L homeolog antibody, beta actin antibody, POTE ankyrin domain family member F antibody, actin, beta like 2 antibody, actin, cytoplasmic 1 antibody, ACTB antibody, Actb antibody, actb antibody, LOC100174883 antibody, LOC100304816 antibody, Act5C antibody, ACTG1 antibody, actb1 antibody, actb.L antibody, LOC100136352 antibody, POTEF antibody, ACTBL2 antibody, LOC109073280 antibody
    背景
    Beta-Actin(ACTB) also known as BETA-ACTIN or ACTIN, CYTOPLASMIC, 1, is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Ueyama et al.(1996) used fluorescence in situ hybridization to map ACTB to 7p22. By PCR of somatic cell hybrid DNAs, they mapped 4 ACTB pseudogenes to other chromosomes. Karakozova et al.(2006) found that arginylation of beta-actin regulates cell motility. The majority of Ate1-null cells appeared smaller than wildtype cells and were apparently unable to form a lamella during movement along the substrate. Karakozova et al.(2006) concluded that arginylation of beta-actin apparently represents a critical step in the actin N-terminal processing needed for actin functioning in vivo.

    Synonyms: A26C1A antibody|A26C1B antibody|ACTB antibody|ACTB_HUMAN antibody|Actin cytoplasmic 1 antibody|Actx antibody|b-actin antibody|beta cytoskeletal actin antibody|Beta-actin antibody|E430023M04Rik antibody|MGC128179 antibody|PS1TP5 binding protein 1 antibody|PS1TP5BP1 antibody
    UniProt
    P60709
    途径
    Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
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