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FGF23 抗体 (AA 48-251)

This anti-FGF23 antibody is a 兔 多克隆 antibody detecting FGF23 in WB. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3044523
发货至: 中国

Quick Overview for FGF23 抗体 (AA 48-251) (ABIN3044523)

抗原

See all FGF23 抗体
FGF23 (Fibroblast Growth Factor 23 (FGF23))

适用

  • 73
  • 24
  • 16
小鼠

宿主

  • 63
  • 33
  • 2

克隆类型

  • 67
  • 31
多克隆

标记

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  • 2
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  • 2
  • 2
  • 1
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  • 1
  • 1
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This FGF23 antibody is un-conjugated

应用范围

  • 60
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  • 24
  • 23
  • 9
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  • 2
  • 1
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 19
    • 9
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    • 1
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    AA 48-251

    原理

    Anti-FGF23 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-FGF23 Antibody Picoband® (ABIN3044523). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1% and 94.6% amino acid (aa) sequence identity with human and rat FGF23, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse
    1. "Entrez Gene: FGF23 fibroblast growth factor 23". 2. Fukumoto S (2008). "Physiological regulation and disorders of phosphate metabolism--pivotal role of fibroblast growth factor 23". Intern. Med. 47 (5): 337-43. 3. Yamashita T, Yoshioka M, Itoh N (October 2000). "Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain". Biochem. Biophys. Res. Commun.277 (2): 494-8.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Ji, Ling, Zhang, Chou, Yang, Wang, Yin, Wu, Yu: "MicroRNA-296 mediated corneal neovascularization in an animal model of corneal burns after alkali exposures." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 139-144, (2018) (PubMed).

  • 抗原

    FGF23 (Fibroblast Growth Factor 23 (FGF23))

    别名

    Fgf23

    背景

    Synonyms: Fibroblast growth factor 23,FGF-23,Fgf23,

    Tissue Specificity: Mainly expressed in the brain and thymus at low levels. In brain, preferentially expressed in the ventrolateral thalamic nucleus.

    Background: Fibroblast growth factor 23?or?FGF23?is a?protein?that in humans is encoded by the?FGF23?gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

    分子量

    34 kDa

    基因ID

    64654

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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